The Obsessive Compulsive Disorder (TOC) is a mental illness caused by anxiety or anguish, and characterized by the presence of persistent thoughts, or rather, obsessions. These constant thoughts are suppressed with new thoughts or actions, also known as compulsions. Compulsions are defined as acts provoked in response to the obsession that pretend to avoid anxiety or anguish.
The word 'refractory' applies to diseases that do not react to treatment. About 60% of patients with OCD do not respond to the first treatment. The alternatives in these cases could be an increase in the dose or change the medication completely. In this sense, a new test reported on patients who are resistant to OCD treatment and who could respond better to an increase in doses of medications combined with medicinal cannabis.
Improve refractory obsessive-compulsive disorder
In 2008, a group of researchers published an article in the American Journal of Psychiatry. In this article, the researchers highlighted the experiences of two patients with refractory obsessive-compulsive disorder, a man and a woman, after the administration of synthetic THC.
The woman was prescribed an antidepressant, a selective serotonin reuptake inhibitor, and psychological therapy to manage her OCD and depression for 8 months, but it did not work. When switching to a new antidepressant, tricyclic antidepressant, it resulted in a partial response after 12 weeks of treatment. Interestingly, the patient reported that when she smoked cannabis, her symptoms were relieved. Based on this personal experience, it was decided to supplement their current treatment with synthetic THC. In just 10 days, his symptoms of obsessive-compulsive disorder decreased, and his severity disease score improved by 50%.
On the other hand, the man was prescribed antipsychotics, either in monotherapy or in combination with an antidepressant, selective inhibitor of serotonin reception, without success either. The partial response to their psychotic and refractory symptoms of obsessive-compulsive disorder was only possible with an atypical antipsychotic medication (clozapine) in combination with an antidepressant (selective inhibitor of serotonin reuptake). Subsequently, the patient tried to switch to another antidepressant (tricyclic antidepressant) and additional electroconvulsive therapy, but did not improve. In your case, after the addition of Synthetic THC Ongoing medication, symptoms of refractory obsessive-compulsive disorder were reduced by 2 weeks, and their disease score improved by 35%. No side effects were reported in these patients.
Based on these two cases, the researchers hypothesized that cannabinoids are definitely useful in the treatment of the symptoms of people with refractory OCD.
In 2010, a clinical study was published later in the Journal Behavioral Pharmacology, describing the observation of the effects of cannabidiol (CBD) in rodents, subject to an animal model proposed to reflect compulsive behavior. In this study, the researchers found that CBD, a component of cannabis that has anxiolytic effects, in both animals and humans, could significantly reduce the symptoms associated with animal behavior for a significant duration, since the effects of CBD were still present after 7 days of administration. A similar decrease was found using benzodiazepine diazepam and paroxetine, a selective inhibitor of serotonin reuptake. However, the effect of diazepam was no longer present after 7 days. Then, the results suggest a potential role of cannabinoids in the cannabinoid system to control compulsive behavior.
In general, these studies demonstrated a therapeutic potential of cannabinoids to reduce obsessive compulsive disorders. However, new studies are needed to definitively validate its usefulness or not.
Did you like this post? Make an assessment. This post has been made based on existing research until the date of publication of the article. Due to the increase of studies around medical cannabis, the information exposed may vary over time and we will inform in subsequent writings.
 Hirschtritt, M.E., Bloch, M.H., & Mathews, C.A. (2017). Obsessive-Compulsive Disorder. JAMA, 317 (13), 1358. doi: 10.1001 / jama.2017.2200
 Schindler, F., Anghelescu, I., Regen, F., & Jockers-Scherubl, m. (2008). Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol. American Journal of Psychiatry, 165 (4), 536-537.doi: 10.1176 / appi.ajp.2007.07061016
 Casarotto PC, Gomes FV, Resstel LB, Guimaraes FS. Cannabidiol inhibitory effect on marble-burying behavior: involvement of CB1 receptors. Behav Pharmacol 2010; 21: 353-358.
Here’s what you want to know before seeing your regional medical dispensary:You may require a doctor’s recommendation, medical cannabis certificate, and/or whatever proper documentation is needed by your condition. Typically, you need to be 18 or older to qualify for a medical consent, but exceptions could be made in some states for minors with especially debilitating conditions. You will usually register with a medicinal dispensary. This is to maintain your medical cannabis recommendation or certification on file for legal and regulatory purposes. There will be a waiting space. This will be to control the flow of patients and product, but a straightforward dividing wall gives patients solitude and direct one-on-one contact using a budtender to candidly discuss medical issues. Many times, but not always, your purchases will be monitored by medical dispensaries. This procedure can assist budtenders and patients track effective medicine in addition to possess a living listing of producers and products for future reference and follow up. Medicinal dispensaries usually permit you to smell and examine the buds before buy. This might vary from state-to-state.
Yes, municipal approval is required prior to the AGLC will subject a retail cannabis license. Applicants must get in touch with their planned municipality to learn requirements regarding municipal retail cannabis laws, zoning requirements, land-use limitations, and place requirements concerning how near a retail store can be to a provincial medical care facility, college, or parcel of land designated as a college book.
Keep non-medical cannabis legal Adults who are 19 years or older are able to:Have up to 30 gram of legal dried cannabis or the equivalent in their own person. Share up to 30 gram of legal cannabis with other adults in Canada. Purchase cannabis products from a Yukon Liquor Corporation licensed merchant. Grow up to four crops per household. It’s illegal to provide non invasive cannabis to anyone under the age of 19 and also for anyone below the age of 19 to have any amount of anti inflammatory cannabis in Yukon.It is dangerous and illegal to drive while under the influence of cannabis or other intoxicants.