The osteoarthritis or chronic degenerative arthropathy is the degeneration of the cartilage of the joints without inflammation or infection. In the joints, the cartilage breaks and disappears, this causes bone growths that interfere with the movement.
It is a quite frequent alteration. In fact, 85% of people over 70 are diagnosed with this disease. It is characterized by difficulty in making movements and due to daytime pain. Repetitive trauma (mechanical), obesity (metabolic) or menopause (hormonal) are the causes of osteoarthritis.
The arthritis is a Chronic inflamation and severe of the joints of the body without chronic damage of the cartilage. When it affects only one joint, this condition is known as monoarthritis. If we talk about 2 to 4 damaged joints, we talk about oligoarthritis and when there are more damaged joints, we talk about polyarthritis. These are characterized by severe tendon pain, redness, warmth sensation, swelling, body aches and stiffness. Its origin can be: infectious or rheumatic (rheumatoid: it is an autoimmune disease that can have several extra-articular manifestations).
The rheumatoid polyarthritis It is the first chronic polyarthritis, it is found mainly in adults and there are currently more than 60 million people affected worldwide. The mechanisms that lead to its appearance are genetic and environmental. A dysfunction in the immune system activates the cells that normally defend the body against infections and create antibodies that attack the synovial membrane, a protective tissue of the joints. This damages cartilage, muscle tendons and bones. Therefore, the areas of union between the bone ends show deformations.
Medicinal cannabis as a treatment for osteoarthritis
Endocannabinoid System (SEC), with ligands and endogenous receptors. These receptors also react to cannabidiol or tetrahydrocannabinol (the chemical compounds found in the cannabis plant). This interaction causes changes in the cells of various parts of the body and is essential for the body to function normally.
Cannabidiol (CBD) is responsible for several therapeutic properties. It can be used to treat inflammation, anxiety, nausea, seizures, or pain, among other symptoms. In this sense, the scientific community recognizes that CBD can activate cannabinoid receptors in mammals without secondary or psychoactive effects.
Recent studies have shown an active participation of the Endocannabinoid System in the physiopathology of the osteoarthritis. The results reinforce the interest in cannabinoids for this disease, especially to regulate the functions of the joints and for being a good analgesic and anti-inflammatory.
Another publication showed preclinical evidence that the CB2 receptors of the endocannabinoid system were a very close receptor to CBD, and that this attenuates peripheral immune cells and modulates central pain sensitivity, particularly in the knee.
Medicinal cannabis to treat rheumatoid arthritis
A group of researchers discovered cannabinoid receptors (CB1 and CB2) in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. These data could be an important goal in terms of medication for the treatment of pain and inflammation.
The multiple properties of medicinal cannabis they make it particularly effective when treating various diseases, insofar as it is used in the correct doses and with quality products.
Did you like this post? Make an assessment. This post has been made based on existing research until the date of publication of the article. Due to the increase of studies around medical cannabis, the information exposed may vary over time and we will inform in subsequent writings.
Here’s what you need to know before visiting your local medical dispensary:You may require a physician’s recommendation, medical cannabis certificate, or whatever appropriate documentation is needed by your state. Typically, you must be 18 or older to be eligible for a medical authorization, but exceptions could be made in some states for minors with especially debilitating problems. You will usually enroll with a medicinal dispensary. This is to keep your medical cannabis recommendation or certification on file for legal and regulatory purposes. There will be a waiting space. This will be to control the flow of product and patients, but a straightforward dividing wall gives patients solitude and direct one-on-one contact with a budtender to discuss medical problems. This procedure can assist budtenders and patients monitor effective medication as well as have a living listing of producers and products for future reference and follow up. Medicinal dispensaries usually allow you to smell and analyze the buds before purchase. This might differ from state-to-state.
DOES AN APPLICANT NEED MUNICIPAL APPROVAL BEFORE RECEIVING A RETAIL CANNABIS LICENSE? Yes, municipal approval is required before the AGLC will issue a retail cannabis license. Applicants should get in touch with their planned municipality to find out requirements regarding municipal retail cannabis legislation, zoning requirements, land-use limitations, and place requirements concerning how near a retail store is into a provincial health care facility, school, or parcel of land designated as a school reserve.
Keep non-medical cannabis legal Adults that are 19 years or older are able to:Possess up to 30 g of authorized dried cannabis or the equivalent on their person. Share up to 30 gram of legal cannabis along with other adults in Canada. Buy cannabis goods from a Yukon Liquor Corporation licensed merchant. Grow up to four crops per family. It’s illegal to present non invasive cannabis to anyone under the age of 19 and also for anyone under the age of 19 to possess any amount of non-medical cannabis in Yukon.It is dangerous and illegal to drive while under the influence of cannabis or other intoxicants.