Lupus is a chronic autoimmune disease, which is estimated to affect about 5 million people around the world. It is more common in women (90%) than in men and is characterized by inflammation (severe and chronic) of different tissues of the body, including the joints, kidneys, lungs, skin, blood and heart. The etiology is unknown but genetic predisposition and environmental risk factors are implicated.
The mechanism of this condition involves a immune response of autoantibodies against healthy and unhealthy cells. Patients usually suffer severe pain, fatigue, hair loss, seizures, … It is not a contagious pathology but it has no cure, and the prescribed medication often causes negative side effects (sometimes worse than those caused by the disease itself) .
Although there is a lack of research on the use of medical cannabis to treat these symptoms of lupus, the anti-inflammatory and analgesic properties of certain cannabinoids make them a perfect alternative to conventional medications for this condition.
Types of lupus
Systemic Lupus Erythematosus (SLE): It is considered as the most common form of Lupus. The symptoms are inflammation of the kidneys, brain and blood vessels (inside the brain). It can also cause hardening of the arteries. These complications cause changes in mood, behavior, memory problems, kidney failure, stroke, seizures, among other effects.
Discoid Erythematosus Lupus (LED): It is usually limited to the skin and is often caused by direct sunlight or fluorescent lights. Symptoms include lesions and rashes, such as discoid (disc-shaped, raised, red) eruptions. A common sign is the butterfly-shaped rash around the cheeks and the bridge of the nose.
Drug-induced erythematosus lupus (LEIF): This type of lupus is caused by various pharmaceutical products. The symptoms are similar to those present in the SLE and these decrease 6 months after the patient has stopped taking the medication that is causing the disease.
Neonatal Lupus: This disease is not a form of lupus, but rather a rare pathology that affects the growing fetus within the pregnant woman, who suffers from lupus. Symptoms can be liver problems, rashes or low blood cell counts at birth. Generally, it disappears several months later.
Lupus and cannabinoid treatments
The Current treatments for Lupus they include antimalarial, immunosuppressive, non-steroidal anti-inflammatory, corticosteroid and biological medications. Although these substances can be incredibly useful for many patients, they can also cause several negative side effects on the kidneys, liver, stomach and heart or even cause eye damage, infertility, nausea, depression and diabetes. In addition, patients always spend months trying to find the right mix of drugs for their symptoms, causing the development of an intolerance towards them as a result and sometimes all these options fail, so it is necessary to find new pharmaceutical products.
Several studies have proven the anti-inflammatory effects of cannabinoids. In addition, it has been observed that cannabinoids protect against the deterioration of autoimmune diseases, such as arthritis. Although the reactions in lupus have been very little studied, it can be assumed that CBD could have the same anti-inflammatory benefits. In fact, it has been observed that CBD can calm the inflammation of skin rashes and reduce redness. Another recent discovery focuses on the flavonoids found in cannabis. One in particular, Cannaflavin A, has been shown to be an incredibly powerful anti-inflammatory molecule (up to 30 times more effective than Aspirin).
Other important property of the CBD is its analgesic potential. When CBD is given in the correct dose, it can help relieve pain. This has been confirmed in several studies on neuropathic pain and pain in cancer. Again, a calming action can be inferred for patients suffering from lupus. Therefore, instead of taking opioid-based analgesics, CBD could become a better, safer, natural and non-addictive resource. Drugs derived from Opium can cause addiction, dependence, depression, anxiety and others.
In conclusion, more studies are needed on cannabinoids and this autoimmune disease, but its anti-inflammatory, analgesic and non-toxic properties could make CBD an attractive option, instead of the classic recommendations. In addition, as far as is known, cannabidiol seems to be the best option to improve the symptoms of lupus.
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* This post has been made based on existing research until the date of publication of the article. Due to the increase of studies around medical cannabis, the information exposed may vary over time and we will inform in subsequent writings.
Here is what you want to know before seeing your regional medical dispensary:You will need a doctor’s recommendation, medical cannabis certification, and/or whatever proper documentation is required by your condition. Typically, you need to be 18 or older to qualify for a medical authorization, but exceptions may be made in some states for minors with especially debilitating problems. You will usually enroll with a medicinal dispensary. This is to maintain your medical cannabis recommendation or certification on file for legal and regulatory purposes. There will be a waiting space. This is to control the circulation of product and patients, but a straightforward dividing wall also gives patients privacy and direct one-on-one contact using a budtender to candidly discuss medical problems. This procedure can help budtenders and patients track effective medicine in addition to possess a living record of producers and goods for future reference and follow-up. Medicinal dispensaries usually permit you to smell and analyze the buds prior to purchase. This may differ from state-to-state.
Yes, municipal approval is necessary prior to the AGLC will subject a retail cannabis license. Applicants must get in contact with their intended municipality to find out requirements concerning municipal retail cannabis legislation, zoning requirements, land-use limitations, and place requirements regarding how near a retail store is to a provincial medical care centre, college, or parcel of land designated as a school reserve.
Keep non-medical cannabis legal Adults who are 19 years or older are able to:Possess up to 30 gram of authorized dried cannabis or the equivalent in their person. Share up to 30 g of legal cannabis with other adults in Canada. Buy cannabis goods from a Yukon Liquor Corporation licensed retailer. Grow up to four crops per household. It is illegal to provide non invasive cannabis to anyone below the age of 19 and also for anyone below the age of 19 to possess any amount of non-medical cannabis in Yukon.It is illegal and dangerous to drive while under the influence of cannabis or other intoxicants.