The Ehlers-Danlos syndrome (SED) they are a group of hereditary genetic conditions that affect the connective tissue in the human body. These levels of cellular organization sustain our bones, skin, blood and other multiple organs.
Ehlers Danlos: symptoms
The symptoms appear when this group of cells has defects, which can vary from mild to dangerous for life. Depending on the symptomatology and the affected areas, there are 13 different classifications in total, 6 of which are the most common:
- Classic SED (SEDc)
- SED Hipomobile (SEDh)
- SED Vascular (SEDv)
- SED Cifoescoliótico (SEDk)
- SED Arthrocalasia (SEDa)
- SED Dermatoparaxis (SEDd)
Mutation in the following genes may cause EDS, although it is not a complete list, it includes: COL1A1, COL1A2, COL3A1, COL5A1 and COL6A2. This permanent alteration in the genome sequence of an organism results in defects in the architecture of collagen or in proteins that interact with this biomolecule. Without these main components, the connective tissue is much weaker, reflecting the presence of an unusual state or symptoms, which vary greatly, but there are some that occur in most cases:
- An abnormally large range of motion in the joints. This situation can lead to other diverse problems such as being at risk of dislocation.
- Hypotonia Weak muscle tone. It implies reduced muscle strength, which is associated with poor development of important motor skills, as well as walking.
- Skin too soft, elastic and fragile. This fragility can lead to tearing of the skin, the wounds could reopen without any effort, the scars seem to extend over time and the person in question could bruise very easily. The patient may also have excess and loose skin.
- The blood vessels could break out of nowhere, causing internal bleeding inside the organs like the heart.
- Curvature of the spine. Medical case in which the person's spine has a lateral curvature.
Other manifestations are complications during pregnancy, fatigue, headaches, gastrointestinal diseases and nervous disorders.
Cannabinoids and the Ehlers-Danlos Syndrome
According to one study, about 90% of those with this syndrome reported some form of chronic pain, more prevalent in cases where the muscles are constantly tense, or there is inflammation of the joints, and dislocation or subluxation ( partial dislocation) repetitive and unpredictable.
A Swedish group of researchers reported that about 75% of patients suffer from anxiety and 25% from depression due to this disease. In general, the cure is unknown but there are treatments that prevent further deterioration and improve the quality of life. Tools such as analgesics, physiotherapy, orthopedic instruments and psychological therapy could help.
An intervention with cannabinoids could be an alternative to help with pain, anxiety and depression, all in one. The analgesic, anti-inflammatory, anxiolytic and antipsychotic properties of cannabidiol (CBD) they have been studied extensively. This cannabinoid is considered to have a low risk of addiction and without side effects.
In addition, opioid-based analgesics can be discontinued or reduced when taking CBD, because it increases the activity of analgesics, making it possible to avoid addiction, increased tolerance or liver damage. It was found in a Brazilian study that the CBD managed to reduce almost all signs of Generalized Social Anxiety Disorder (SAD), one of the most common forms of anxiety disorders.
Apart from medical research, there are also endless personal testimonies from several patients suffering from the Ehlers-Danlos Syndrome, explaining their testimony with the use of medicinal cannabis. These pieces of anecdotal evidence should not be ignored since no one knows these sensations better than the patients themselves.
In conclusion, it is necessary to investigate more about the Ehlers-Danlos Syndrome. However, observing some specific symptoms, CBD could be an excellent prescription due to its analgesic, anxiolytic and anti-inflammatory actions.
Did you like this post? Make an assessment. This post has been made based on existing research until the date of publication of the article. Due to the increase of studies around medical cannabis, the information exposed may vary over time and we will inform in subsequent writings.
Here’s what you need to know before visiting your regional medical dispensary:You will need a doctor’s recommendation, medical cannabis certificate, and/or whatever proper documentation is required by your condition. Typically, you must be 18 or older to qualify for a medical authorization, but exceptions may be made in some states for minors with especially debilitating problems. You will often enroll with a medicinal dispensary. This is to maintain your medical cannabis recommendation or certificate on file for legal and regulatory purposes. There will be a waiting space. This is to control the flow of patients and product, but a straightforward dividing wall gives patients privacy and direct one-on-one contact using a budtender to discuss medical issues. Many times, but not always, your purchases will be monitored by medical dispensaries. This procedure can help budtenders and patients monitor effective medication in addition to possess a living record of producers and products for future reference and follow up. Medicinal dispensaries usually allow you to smell and analyze the buds prior to buy. This may differ from state-to-state.
Yes, municipal approval is required before the AGLC will subject a retail cannabis license. Applicants must get in contact with their intended municipality to learn requirements regarding municipal retail cannabis legislation, zoning requirements, land-use restrictions, and place requirements regarding how close a retail store is to a provincial health care facility, school, or parcel of land designated as a college reserve.
Keep non-medical cannabis legal Adults that are 19 decades or older are in a position to:Possess up to 30 g of legal dried cannabis or the equivalent in their own person. Share up to 30 gram of legal cannabis with other adults in Canada. Purchase cannabis products from a Yukon Liquor Corporation licensed retailer. Grow up to four plants per household. It is illegal to provide non invasive cannabis to anyone under the age of 19 and also for anyone under the age of 19 to possess any quantity of non-medical cannabis in Yukon.It is dangerous and illegal to drive while under the influence of cannabis or other intoxicants.